Toxic synovitis

Toxic synovitis is a condition affecting children that causes hip pain and limping.

Alternative Names

Synovitis - toxic; Transient synovitis

Causes, incidence, and risk factors

Toxic synovitis is a frequent cause of limping with hip pain in children. It occurs in children prior to the onset of puberty and is a transient arthritis of the hip that usually resolves on its own. Its cause in not known but boys are affected more frequently than girls (approximately 4 to 1). Symptoms are usually mild and generally include hip pain and a slight limp. The hip pain almost always involves only one side (unilateral). A low grade fever (usually less than 101 degrees) may be an early symptom. Aside from the hip discomfort, the child does not usually appear ill. Toxic synovitis is a diagnosis of exclusion, which means that it is diagnosed when other, more serious conditions, have been ruled out. In children there are three potentially serious diseases that can cause hip pain and limp: septic hip, slipped capital femoral epiphysis, and Legg-Calve-Perthes disease. Once these other diagnoses have been excluded, then the diagnosis of toxic synovitis (which is the most common of all these diseases) is usually made.

Signs and tests

  • ultrasound
  • of the hip will demonstrate a joint effusion
  • X-ray
  • of the hip (expected to be normal)
  • ESR
  • may be slightly elevated
  • complete blood count (may show increased white cells)
  • Other test occasionally done to rule out other causes of hip pain:
  • aspiration
  • of fluid from the hip joint
  • bone scan
  • MRI
  • Treatment

    Treatment often includes limiting activity to make the child more comfortable. However, there is no danger associated with performing normal activities. Nonsteroidal anti-inflammatory medications (NSAIDS) may be prescribed to reduce pain.

    Expectations (prognosis)

    The hip pain resolves within a week to 10 days.

    Complications

    Toxic synovitis is a self-limited disease with no expected long-term complications.

    Calling your health care provider

    Call for an appointment with your child's health care provider if your child has unexplained hip pain or a limp, with or without associated fever . If your child has a diagnosis of toxic synovitis you should call if the hip pain persists longer than 10 days, if the pain gets worse or if a high fever develops.

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